Hydrocodone can produce miosis, euphoria, physical and psychological dependence. Do not flush down a toilet or pour down a drain unless you are told to do so. Dermatologic: Flushing, hyperhidrosis, pruritus, rash. See the end of this Medication Guide for a complete list of ingredients in hydrocodone bitartrate and homatropine methylbromide. Adults 18 years of age and older: One (1) tablet or 5 mL of the oral solution every 4 to 6 hours as needed; not to exceed six (6) tablets or 30 mL in 24 hours. breast milk, and, therefore, should be used cautiously by nursing mothers. Adolescents 18 years: 5 mg/1.5 mg (1 tablet) PO q4-6hr, up to 30 mg/9 mg (6 tablets) in 24 hr. Overall, the effects of opioids appear to be modestly immunosuppressive. Carcinogenicity studies were conducted with codeine, an opiate related to hydrocodone. Do not store in a bathroom. Hydrocodone is an opioid cough suppressant (antitussive) that works on certain centers in the brain to stop the urge to cough. Psychic dependence, physical dependence and tolerance may develop upon repeated administration of opioids; therefore, hydrocodone bitartrate and homatropine methylbromide tablets should be prescribed and administered with caution. Hemodialysis is not routinely used to enhance the elimination of hydrocodone from the body. Clinical studies have not been conducted with hydrocodone bitartrate and homatropine methylbromide in geriatric populations. Hydrocodone-Homatropine is a cough prescription cough-suppressant that comes in both syrup and tablet form. Therefore, before using this product, tell your doctor or pharmacist about all your products. The chemical name for homatropine methylbromide is 8-Azoniabicyclo [3.2.1]octane,3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-,bromide, endo-. For treating opioid related issues in . Hydrocodone bitartrate and homatropine methylbromide tablets should be used with caution in pediatric patients 6 years of age and older (see WARNINGS Pediatric Use). Primary attention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and the institution of assisted or controlled ventilation. Tablet. lead to overdose and death. Infants exposed to hydrocodone bitartrate and homatropine methylbromide through breast milk should be monitored for excess sedation and respiratory depression. Available for Android and iOS devices. Tell your doctor about the allergy and DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. The co-ingestion of alcohol with hydrocodone bitartrate and homatropine methylbromide may result in increased plasma levels and a potentially fatal overdose of hydrocodone, Hydrocodone bitartrate and homatropine methylbromide is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus, The concurrent use of anticholinergics with hydrocodone bitartrate and homatropine methylbromide may produce paralytic ileus. Abuse and addiction are separate and distinct from physical dependence and tolerance. take medicines called "anticholinergics" used to treat certain health problems including asthma, chronic obstructive pulmonary disease (COPD), or stomach problems. This often ends up being at the recommended dose of 2.5 to 10 mg per dog two to four times daily. Hydrocodone bitartrate and homatropine methylbromide contains hydrocodone, a Schedule II controlled substance. Be ready to tell or show what was antitussive. A limited number of pregnancies have been reported in published observational studies and postmarketing reports describing hydrocodone use during pregnancy. Package Description. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. Hey guys so I got this bottle of hydrocodone-homatropine cough syrup. Effects on the Gastrointestinal Tract and Other Smooth Muscle. Next, pick a pharmacy to get a coupon. other drugs that inhibit monoamine oxidase, for example, linezolid (Zyvox). Do not take 2 doses at the same time or extra doses. Hydrocodone bitartrate and homatropine methylbromide tablets may produce doserelated respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSAGE). MAOI interactions with opioids may manifest as serotonin syndrome or opioid toxicity (e.g., respiratory depression, coma). questions, talk with your doctor or pharmacist. BACKGROUND. As most agents in the 5-ring morphinan group of semi-synthetic opioids bind plasma protein to a similar degree (range 19% [hydromorphone] to 45% [oxycodone]), hydrocodone is expected to fall within this range. The hydrocodone in hydrocodone bitartrate and homatropine methylbromide may result in constipation or obstructive bowel disease, especially in patients with underlying intestinal motility disorders. Avoid driving a car or operating machinery during treatment with hydrocodone bitartrate and homatropine methylbromide. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Postmarketing events seen in patients older than 6 years of age include accidental overdose, cardio-respiratory arrest, death due to drug toxicity, non-accidental overdose, and overdose. Homatropine / hydrocodone systemic 1.5 mg / 5 mg (N 350). dependence can occur when used long-term. Avoid the use of hydrocodone bitartrate and homatropine methylbromide if you: What are the possible side effects of hydrocodone bitartrate and homatropine methylbromide? The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and to electrical stimulation. These can include: dry mouth, loss of visual accommodation, photophobia, and difficulty in urination. No specific drug interaction studies have been conducted with hydrocodone bitartrate and homatropine methylbromide. Prolonged use of opioids during pregnancy may cause neonatal opioid withdrawal syndrome [see Warnings and Precautions (5.13), Clinical Considerations]. Chronic use of opioids may influence the hypothalamic-pituitary-gonadal axis, leading to androgen deficiency that may manifest as low libido, impotence, erectile dysfunction, amenorrhea, or infertility. Patients receiving opioids, antihistamines, antipsychotics, antianxiety agents or other CNS depressants (including alcohol) concomitantly with hydrocodone bitartrate and homatropine methylbromide tablets may exhibit an additive CNS depression. It is not known whether these effects on fertility are reversible [see Use in Specific Populations (8.3)]. combinations may lead to confusion, high blood pressure, tremor, hyperactivity, Wean the patient off of the opioid to allow adrenal function to recover and continue corticosteroid treatment until adrenal function recovers. Benefit to risk ratio should be carefully considered especially in the pediatric population with respiratory embarrassment (e.g., croup) (see PRECAUTIONS). Review/update the information highlighted below and resubmit the form. Hydrocodone produces dose related respiratory depression by directly acting on the brain stem respiratory center that controls respiratory rhythm and may produce irregular and periodic breathing. It has a molecular weight of 494.50 and has the following chemical structure: C18H21NO3 C4H6O6 2H2O MW 494.490. Anticholinergic agents can also precipitate acute narrow angle glaucoma. Keep all drugs in a safe place. The NDC Code 10702-055-01 is assigned to a package of 100 tablet in 1 bottle of Hydrocodone Bitartrate And Homatropine Methylbromide, a human prescription drug labeled by Kvk-tech, Inc.. Monitor these patients for signs of hypotension after initiating hydrocodone bitartrate and homatropine methylbromide. How to get adderall prescribed from doctor . Read all information given to you. What is hydrocodone bitartrate and homatropine methylbromide? Other opioid-induced effects may include a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase. If the response to an opioid antagonist is suboptimal or only brief in nature, administer additional antagonist as directed by the product's prescribing information. Tablet (Hydrocodone 5 mg and homatropine 1.5 mg per tablet): Children 6 to 11 years: Oral: One-half ( 1 / 2) tablet every 4 to 6 hours as needed; maximum daily dose: 3 tablets/24 hours. taken, how much, and when it happened. Hydrocodone may produce marked drowsiness and impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. 5mg/1.5mg . There are no adequate studies of hydrocodone in pregnant women. The instructions on bottle say 1 teaspoon every 4 hours for cough. The above information is intended to supplement, not . Prolonged use of opioid analgesics during pregnancy for medical or nonmedical purposes can result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth. Hydrocodone. Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opiod drugs. Opioid drugs can put you at risk for addiction, abuse, and misuse. cough suppressant that is similar to codeine, oxycodone, morphine, methadone, Dosage Considerations Should be Given as Follows: If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Zutripro (hydrocodone bitartrate, pseudoephedrine, chlorpheniramine) TussiCaps (hydrocodone polistirex, chlorphineramine polistirex) 180 capsules/tablets per 90 days Tussigon tablets (hydrocodone bitartrate, homatropine) Tuxarin ER tablets (codeine, chlorpheniramine) Drug with approved MFE only Quantity FlowTuss 64 ounces (1920 mL) per 90 days cough in adults and in children 6 years of age and older. RxNorm, The chemical name for hydrocodone bitartrate is morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl, (5)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1), hydrate (2:5). It is used primarily as a cough suppressant (antitussive) in dogs, working on receptors within the brain. have had a brain tumor or other brain problems, have constipation or other bowel problems, have glaucoma (increased pressure in eyes), have problems with your urinary tract or difficulty urinating, are pregnant or plan to become pregnant. Using this medicine (hydrocodone and homatropine tablets) for a long time during pregnancy may lead to withdrawal in the newborn baby. The use of hydrocodone bitartrate and homatropine methylbromide tablets is not recommended for use in children less than 6 years of age because of the risk of fatal respiratory depression (see ADVERSE REACTIONS Respiratory Depression). 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